Mitochondrial DNA (mtDNA) is actively removed during spermatogenesis in a conserved process that enforces the uniparental ...

Malic acid is known to inhibit the development of kidney stones. The researchers concluded that malic acid supplementation might help treat calcium kidney stones. A 2024 study of malic acid, citric ...

In still other cases, resistance to therapies is caused by further changes to mitochondrial metabolism that reduce treatment effectiveness. Examples of this include upregulating the anti-apoptotic ...

Recent studies have shown that citrate, an intermediate metabolite of the tricarboxylic acid (TCA) cycle ... within the mitochondria and not exchanged with the extracellular space. Citrate is ...

ABSTRACT: GSPT2 (G1 to S phase transition protein 2) has emerged as a critical regulator of the cell cycle and has garnered increased attention for its role in tumor biology in recent years. This ...