CRISPR Snips Away Extra Chromosomes, Offering New Hope for Down Syndrome Treatment
Scientists are exploring gene editing as a way to correct trisomy at the cellular level. Using CRISPR-Cas9, researchers ...
3D structure of the social amoeba genome sheds light on the transition to multicellularity
Each cell of the human body contains two meters of DNA. The whole secret lies in the intricate three-dimensional arrangement that allows DNA strands to be efficiently organized and compacted within ...
In vitro reconstitution of meiotic DNA double-strand breaks: A long-standing challenge solved
In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks ...
Digging into a decades-old hepatitis B mystery suggests a new potential treatment
In their effort to answer a decades-old biological question about how the hepatitis B virus (HBV) is able to establish ...
Live Science on MSN6d
Norrie disease: The rare genetic disorder that makes people go blind and deaf
Norrie disease is an extremely rare, inherited genetic disorder that causes vision loss and was first described in Denmark in ...
eLife12d
Genome Restructuring around Innate Immune Genes in Monocytes in Alcohol-associated Hepatitis
The manuscript addresses the 3D chromatin architecture in monocytes from patients with alcohol-associated hepatitis and its relationship to enhanced transcription of innate immune genes. While the ...
Simple treatment can save lives for men with a common chromosomal disorder
More than half of all men with Klinefelter syndrome (KS) are unaware that they have the condition. Among those who do receive ...
eLife14d
Enalapril mitigates aging by targeting antioxidative genes via phosphorylated Smad1/5/9
In summary, enalapril significantly mitigated multiple pathological markers associated with aging, including lipid droplets, amyloid, glycogen deposition, and fibrosis, in the brain, kidneys, liver, ...
ScienceAlert22d
Octopuses May Have The Oldest Sex Chromosomes in The Animal Kingdom
Cephalopods may have the oldest sex chromosomes of any animal, according to a new discovery in the octopus genome. That's a big deal given that scientists didn't know until now if these oddball ...
SciELO23d
Minimally differentiated acute myeloid leukemia with ring/marker derived from chromosome 7 in a child with Down syndrome
Ring chromosome formation may occur through breaks in the chromosome arms and fusion of the proximal broken ends, leading to the loss of distal material. In addition, rings may be formed by telomere ...
Science Daily23d
Octopuses have some of the oldest known sex chromosomes
Researchers have identified a sex chromosome in the California two-spot octopus. This chromosome has likely been around for 480 million years, since before octopuses split apart from the nautilus ...
techexplorist23d
A major milestone in synthetic biology: Completion of the final chromosome in synthetic yeast genome
Macquarie University researchers and an international team have completed the final chromosome in the world’s first synthetic yeast genome, a significant milestone in synthetic biology. This ...