Highlights: NUZ-001 and its active metabolite NUZ-001 Sulfone demonstrated significant neuroprotective effects in a zebrafish ...

7 Data were presented showing that when chorea, rheumatic polyarthritis and carditis occur in the same patient, chorea tends to appear later — up to several months later — than the other two ...

The Huntington disease (HD) Digital Motor Score (HDDMS), which is derived from smartphone sensor-based motor tests included ...

A five-minute smartphone test using balance and tapping can accurately detect early motor symptoms of Huntington’s disease, providing a faster, more accessible way to track progression and support ...

SOM3355 (bevantolol hydrochloride) hit its objectives in a phase 2 trial in patients with Huntington's disease, improving the involuntary, jerky movements known as chorea that are a key symptom of ...

jerky movements known as chorea, which both affect the dopamine pathway. Crucially, the subgroup analysis was prespecified in the trial protocol, recognising the difficulty of enrolling HD ...

To describe the epidemiology and clinical features of Sydenham’s chorea in the Aboriginal population of northern Australia a review was conducted of 158 episodes in 108 people: 106 were Aborigines, 79 ...

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