Johns Hopkins University School of Medicine researchers have discovered a dual regulatory mechanism safeguarding mitochondrial integrity through the combined actions of Parkin–PINK1 and OMA1. The ...

Newly discovered brain cells count each bite before sending the order to cease eating a meal. Columbia scientists have found specialized neurons in the brains of mice that order the animals to ...

Overall, our study underscores the dynamic and cyclical nature of chromosome stiffness, modulated by both the cell cycle and age-related factors. Chromosome compaction is not a random process, but a ...

Recent research reveals how mitochondria act as reservoirs for NAD, supporting cells during increased demand. This insight opens doors to therapeutic strategies for mitigating aging and related ...

As discussed above, centromeres (kinetochores) are located close to SPBs in the interphase of the mitotic cell cycle (Figure 1C). This allocation is suitable for easy connection between microtubules ...

Subdistal appendages (sDAPs) are centriolar elements that are observed proximal to the distal appendages (DAPs) in vertebrates. Despite the obvious presence of sDAPs, structural and functional ...

(B) The cell cycle. The cell cycle can be divided into G0, G1, S, G2 (interphase), and M-phase (mitosis and cytokinesis). Mitosis can be subdivided into prophase (DNA condensation is initiated), ...