Three kinases have been strongly linked to the aberrant phosphorylation of tau, cyclin-dependent kinase 5 (CDK5), glycogen synthase kinase 3β (GSK3β) and extracellular signal-regulated kinase 2 ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Vascular dementia (VaD) is characterized by ...

We thank D. Arnold, S. Mayor, M. Missler, M. Sainlos, P. Scheiffele, and A. Ting for the generous gift of DNA plasmids; M. Munier and S. Benquet for molecular biology ...

Acute respiratory distress syndrome (ARDS) is a neutrophil-dominant disorder with no effective pharmacological therapies. While the cyclin-dependent kinase inhibitor AT7519 induces neutrophil ...

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Natural products (NPs) have historically served as the basis for a variety of therapeutic applications including treatments in the fields of oncology, infectious diseases, and central nervous system ...

School of Life Science and Technology, ShanghaiTech University, Shanghai, China Department of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, Philadelphia, ...