CDC25A, B and C expression and activity is tightly regulated by many mechanisms, including alternative exon splicing, phosphorylation–dephosphorylation cycles, interactions with partners such as ...

At the molecular level, SMYD3 inhibition led to sustained activation of CDC25A within oocytes, facilitating GVBD but impeding the MI-MII transition due to the absence of CDC25A degradation. Moreover, ...

Department of Chemistry, University of Waterloo, Waterloo, Ontario, N2L 3G1, Canada, Department of Biochemistry, Queen's University, Kingston, Ontario, K7L 3N6, Canada, and Department of Biochemistry ...