APC can shuttle between nucleus and cytoplasm. Figure 4: β-catenin accumulates in the nucleus when nuclear export is blocked. Figure 5: APC(1–1,309) can export β-catenin from the nucleus.

Hepatocellular carcinoma (HCC) is the most common primary liver cancer and a leading cause of cancer-related deaths worldwide ...

A turtle’s head seems simple: a hard beak, two bright eyes, and a quilt of scales that protect the skull. Look closer and a ...

This important work supports the role of breast carcinoma amplified sequence 2 (Bcas2) in positively regulating primitive wave hematopoiesis through amplification of beta-catenin-dependent (canonical) ...

CCAL promoted CRC progression by targeting activator protein 2α (AP-2α), which in turn activated Wnt/β-catenin pathway. CCAL induced multidrug resistance (MDR) through activating Wnt/β-catenin ...