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ahajournals.org19d
XBP1 (X-Box–Binding Protein-1)–Dependent O-GlcNAcylation Is Neuroprotective in Ischemic Stroke in Young Mice and Its Impairment in Aged Mice Is Rescued by Thiamet-G
1 To determine whether the XBP1/HBP/O-GlcNAc axis is functional in neurons, as it is in cardiomyocytes, 16 we used TRE-XBP1s;Camk2a-tTA (XBP1s-TG) mice in which neuron-specific expression of transgene ...
Nature27d
Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood
Major psychiatric disorders including schizophrenia (SCZ), bipolar disorder (BPD), major depressive disorder (MDD) and autism are moderately to highly heritable, and increasing evidence is ...
Frontiers4d
Progress of bone marrow mesenchymal stem cell transplantation on neural plasticity in brain
Stem cells are cells with strong proliferation and differentiation abilities. Among all stem cells, bone marrow mesenchymal stem cells (BMSCs) have been extensively studied. BMSCs have the ability to ...
The EMBO Journal24d
Targeted tandem affinity purification of PSD‐95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins
The molecular complexity of mammalian proteomes demands new methods for mapping the organization of multiprotein complexes. Here, we combine mouse genetics and proteomics to characterize synapse ...
Frontiers11d
Transcriptome analysis to identify candidate genes related to mammary gland development of Bactrian camel (Camelus bactrianus)
Introduction: The demand for camel milk, which has unique therapeutic properties, is increasing. The mammary gland is the organ in mammals responsible for the production and quality of milk. However, ...
C&EN26d
Dehydrozingerone Improves Mood and Memory in Diabetic Mice via Modulating Core Neuroimmune Genes and Their Associated Proteins
Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Hajipur 844102, India ...