"Notably, unlike clopidogrel, which is metabolically activated via cytochrome P450 2C19 (CYP2C19), prasugrel is primarily activated through cytochrome P450 3A4 and 2B6," Kang and colleagues wrote.

Oral contraceptives or hormone therapy Medication that uses the cytochrome enzymes called CYP2C19 or CYP3A4 Who should avoid chasteberry? It's unclear, but chasteberry may alter your hormone levels.

Bowen, A. and Nargundkar, S. (2025) Transformational Strategies to Improve the Clinical Trial and Drug Development Process.

Expert Rev Clin Pharmacol. 2012;5(3):319-336. Finally, a recent study suggested that although prasugrel significantly reduces thrombotic events in patients with ACS undergoing PCI because of its ...

CYP2C19*3 is mainly found in the Japanese population. There are also ethnic differences in the frequency of the poor metabolizer phenotype. About 3-5% of Caucasians and 12- 23% of most Asian ...

Hypertrophic cardiomyopathy (HCM), the most common inherited cardiovascular disease, accounts for a substantial number of cases of heart failure and sudden death.1 2 Resting or physiologically ...