Find out more about chemokines and their role in inducing immune response against different diseases, particularly cancer.

miR-221-3p promotes IL-6 and IL-8 secretion in M2-macrophages but suppresses those of IL-10, CXCL13, JAK3, and the activation of pSTAT3. JAK3, a target of miR-221-3p, is involved in mediating the ...

Background: Primary central nervous system lymphoma (PCNSL) is characterized by a lack of specificity and poor prognosis. Further understanding of the tumor heterogeneity and molecular phenotype of ...

Background The determinants of the response to checkpoint immunotherapy in hepatocellular carcinoma (HCC) remain poorly understood. The organisation of the immune response in the tumour ...