Kancera AB (publ) (Kancera) today reports the top-line results from the KANDOVA study, a one-arm, open-label, multi-centre combined phase Ib/IIa study of KAND567 in combination with carboplatin in ova ...

CX3CL1 secreted in the tumor microenvironment serves as a chemoattractant playing a critical role in metastasis of CX3CR1 expressing cancer cells. CX3CR1 can be expressed in both cancer and ...

Fluorescent reporter lines (eg, GFP-CD68 [green fluorescent protein CD68], CX3CR1-GFP [CX3C chemokine receptor 1 green fluorescent protein]) and congenic mice (eg, CD45.1, CD45.2) also allow for ...

1 Department of Nephrology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China 2 Department of Urology, Sir Run Run Shaw Hospital, Zhejiang University School of ...

Background Current treatments with tyrosine kinase inhibitors and immune checkpoint inhibitors have limited efficacy for ...

Microglia are a specialized type of immune cell that accounts for about 10% of all cells within the brain and spinal cord.

This study presents a fast method for generating human microglia from iPSCs, paving the way for breakthroughs in ...

COVID-19 is characterized by dysregulated thrombosis and coagulation that can increase mortality in patients. Platelets are fast responders to pathogen presence, alerting the surrounding immune cells ...

This work was supported by NIH grants R01 DK031036 (to C.R.K.), in part by NIH training grant T32 DK007260 (to W.C.), and in part by the Steno North American Fellowship (NNF23OC0087108) awarded by the ...