Find out more about chemokines and their role in inducing immune response against different diseases, particularly cancer.

Recent studies link Diet Coke and similar drinks to increased risks of heart attack and stroke. Artificial sweeteners like ...

CX3CL1 secreted in the tumor microenvironment serves as a chemoattractant playing a critical role in metastasis of CX3CR1 expressing cancer cells. CX3CR1 can be expressed in both cancer and ...

Objective To study the role of fractalkine (CX3CL1) in chemotactic and adhesive properties of peripheral blood mononuclear cells (PBMCs) in patients with CMi. Methods and results Patients with ...

Mechanistically, the authors found that miR-195 could directly target both CX3CL1 and CX3CR1, and inhibited CX3CR1-mediated neuroinflammation (65). In conclusion, miRNAs can directly or indirectly ...

According to a special issue of the journal Science, the recognition that inflammation is a primary pathophysiologic mechanism in chronic illness is one of the major scientific insights of the ...

Cholangiocytes are highly specialised cells participating in the pathobiology of various liver diseases and recognised to play a crucial role in response to liver injury. Cholangiocytes exhibit ...

aWallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Mölndal, Sweden bDepartment of Psychiatry and Neurochemistry, University of Gothenburg, Mölndal, Sweden ...