When the monkeys were single-celled embryos, scientists had used CRISPR editing tools to silence, or “knock out”, a gene that ...

Doctors harvest stem cells from the patient’s bone marrow and then send them off to a lab, where CRISPR is used to turn up the production of another, functional version of haemoglobin. This version is ...

Myeloid deficiency of the mitochondrial transacetylase tafazzin upregulates mtROS, disrupting UPR and calcium homeostasis, ...

Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to act against tumors, ...

The Graph offers access to competitive and cost-efficient decentralized data sets. The network boasts a 99.99% uptime and 24/7 availability. Central to The Graph’s operations are subgraphs, APIs that ...

For cancer treatment, a new gene would be introduced into cancer cells. This would either cause the cancer cells to die off or prevent them from growing. CRISPR is an example of gene editing that ...

Treatment depends on how deep the melanoma is and whether it has spread. This is called the stage of the cancer. Treatment also depends on your general health and where the melanoma is on your body.

As shown in murine CRISPR/Cas9 cancer models, even rare events disrupting tumour suppressor genes can trigger hepatocellular cancers.60–62 Most recently, we discovered integration of short Inverted ...

1Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-5900 USA 2Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical ...

Citation Format: SDanish Kadir. Harnessing the dual therapeutic approach of CRISPR/CAS9 and CAR-T cell technologies in KRAS mutated solid tumors [abstract]. In: Proceedings of the AACR Special ...

Molecular Cancer Therapeutics publishes articles on the discovery and preclinical development of novel therapeutic agents for oncology, preclinical studies of approved therapeutics, mechanisms of drug ...