When the monkeys were single-celled embryos, scientists had used CRISPR editing tools to silence, or “knock out”, a gene that ...

Doctors harvest stem cells from the patient’s bone marrow and then send them off to a lab, where CRISPR is used to turn up the production of another, functional version of haemoglobin. This version is ...

Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to act against tumors, ...

CRISPR/Cas9 p53 knockdown and its control plasmids were kindly provided by Dr. Qi Zhang; then, the plasmids were transfected into SiHa-sh-KIF2C and SiHa-sh-NC cervical cancer cells, respectively. The ...

Citation Format: SDanish Kadir. Harnessing the dual therapeutic approach of CRISPR/CAS9 and CAR-T cell technologies in KRAS mutated solid tumors [abstract]. In: Proceedings of the AACR Special ...

However, these few parameters are often not enough to understand the complexity of diseases such as cancer. A team of researchers has developed a new approach to this problem using artificial ...

In the realm of genome editing, LNPs have emerged as a potent vehicle for delivering CRISPR/Cas components, offering significant advantages such as high in vivo efficacy. The incorporation of machine ...

9 In addition to its application in infectious diseases, there are several CRISPR-based developments for the diagnosis of other diseases, including cancer, where it is being used to detect cancer ...

a risk factor for cancer. Renaming DCIS is an “ethical imperative,” she has argued, to spare patients undue anxiety and to shift the current treatment paradigm from invasive surgery to active ...

"The number of patients who achieved this pCR improved significantly as a result of nivolumab, an exciting result that points to a new treatment paradigm in this most common type of breast cancer." ...