CFTR is a plasma membrane, cAMP-activated Cl − channel that is expressed in functionally diverse tissues, including kidney, pancreas, intestine, heart, vas deferens, sweat duct and lung. In ...

Recent studies have generated new insights into the mechanisms of pathogen entry into host cells and signal transduction, but very little is known about the bacterial effectors and cellular ...

We provide evidence that Upd2 transport requires Rab5- and Rab7-mediated endocytic sorting and Lbm-dependent vesicle trafficking. Our study thus uncovers an inter-organ communication in the control of ...