The level of CD107a on the NK cells was analyzed prior to and following coculturing with K562 cells to evaluate the developed NK cells further. CD107a expression was determined to increase ...

The following antibodies were used for cell surface staining: anti-human CD107a REA803, anti-human CD14 REA599, anti-human CD19 REA675, anti-human CD27 REA499, anti-human CD3 REA613, anti-human CD45RA ...

Mice (4-week-old) were subjected to total body irradiation (TBI) using a Gamma Cell 40 Exactor Research Irradiator (Best Theratronics), equipped with a 148 TBq 137 Cs source. The irradiation was ...

Bispecific T cell engagers (TcEs) are immunotherapeutic drugs that trigger the destruction of cancer cells by linking T cells to cancer cells through specific surface molecules (antigens). We designed ...

Correspondence to Dr Georg M Lauer, Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston MA 02114, USA; glauer{at}mgh.harvard.edu Objective Chronic HBV ...

My research is focused on understanding neuroendocrine and age associated changes in immune function and inflammatory responses. Immune function decline with age, resulting in increased illness and ...

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Immunodeficient mice reconstituted with a human immune system represent a promising tool for translational research as they may allow modeling and therapy of human diseases in vivo. However, ...