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Novel 3D microphysiological system models pericyte-induced chemoresistance in glioblastoma
Scientists at the Terasaki Institute for Biomedical Innovation (TIBI), led by Dr. Vadim Jucaud (Assistant Professor), have ...
ascopubs.org6d
Immunotherapeutic response score to predict prognosis for unresectable hepatocellular carcinoma with immune checkpoint inhibitors-based conversion treatment.
Effect of cDC2 licensing by CCL5+ Th1 cells following BCL9/BCL9L inhibition on CD8+ T cell cross-priming for enhanced anti-tumor responses. This is an ASCO Meeting Abstract from the 2025 ASCO Annual ...
thorax.bmj20d
Association of increased CCL5 and CXCL7 chemokine expression with neutrophil activation in severe stable COPD
Methods: The expression of CCL5, CXCL1, 5, 6, 7 and 8, CXCR1, CXCR2, CD11b and CD44 was measured in the bronchial mucosa using immunohistochemistry, confocal immunofluorescence, real-time quantitative ...
Frontiers28d
Identification of key genes CCL5, PLG, LOX and C3 in clear cell renal cell carcinoma through integrated bioinformatics analysis
Gene expression analysis of the hub genes based on the TCGA-KIRC cohort, along with K-M survival analysis, Cox regression, and ROC curve analysis, consistently demonstrated that CCL5, LOX, and C3 are ...
C&EN27d
Ultrasound Visualization of Spatiotemporal Autophagy-Regulated Nanodroplets for Amplifying ICB in Melanoma via Remodeling Tumor Inflammatory Microenvironment
Department of Ultrasound and Chongqing Key Laboratory of Ultrasound Molecular Imaging and Therapy, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China Department of ...
eLife13d
Modeling hereditary diffuse leukoencephalopathy with axonal spheroids using microglia-sufficient brain organoids
This study presents valuable findings on the mechanisms underlying a rare brain disease using an organoid system. In this revised version, there are remaining reviewers' comments that are not yet ...