See Letter p.130 But in a dramatic twist, the authors found that interrupting anti-CCL2 therapy accelerated the development of lung metastases and death (Fig. 1). As early as 10 days after ...

Recent advances in cancer research have underscored the critical role of myeloid cells in shaping tumor microenvironments ...

This study presents an important finding on the role of GATA4 in aging and OA-associated cartilage pathology. The evidence supporting the conclusions is compelling, with rigorous in vitro and in vivo ...

rfc.ucl.ac.uk Objective: The chemokine CCL2 has been consistently found to be up-regulated in systemic sclerosis. To explore the potential value of serum CCL2 measurement in disease assessment, we ...

This study aimed to investigate the involvement of the lncRNA Xist–miR-124–CCL2 axis in HIV Tat-exposed microglial cells. Methods: Mouse primary microglial cells were exposed to HIV Tat, and the ...

Microglia, particularly M2 microglia, were enriched in BM lesions and secreted high levels of both IL6 and CCL2. Hypersecretory IL6 reversed the MET process of BC cells by regulating the JAK2/STAT3 ...

gmx.net Objective Monocyte chemoattractant protein-1 (MCP-1, CCL2), the primary ligand for chemokine receptor C–C chemokine receptor 2 (CCR2), is increased in livers of patients with non-alcoholic ...

Moreover, crocin treatment reduced the proliferation of pulmonary arteriole smooth muscle cells (PASMCs). In addition, crocin treatment not only relieved inflammatory cell infiltration and collagen ...

TME Pharma secures binding commitments for €1.7M proceeds from regular bonds repayable in cash during 12-month maturity period The transaction extends financial visibility into May 2026 with ...

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Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN. (A.L.G., M.M.D., A.B.C., K.C.V., A.C.D.) Department of Medicine ...