Unlike a blastocyst in vivo ... but it remained unclear whether this in vitro model could model later stages of human development. That is, until Brivanlou developed a platform to allow blastoids ...

The researchers discovered that blastocyst complementation led to different outcomes in restoring mouse olfactory neural circuits depending on the model used. In instances where mouse neurons were ...

Further cell divisions lead to the formation of the primitive endoderm, which forms a blastocyst. This structure implants around ... Science who led one of the teams that developed a blastoid model.

This transmitochondrial animal model has considerable potential both ... ES cells and injecting them into donor blastocysts.