Background: Most, if not all, of the cellular functions of the BRCA1 protein are mediated through heterodimeric complexes composed of BRCA1 and a related protein, BARD1. Some breast-cancer ...

Using samples from Aspen’s earlier surgery in the Philippines, St. Jude researchers discovered a rare mutation in a gene called BARD1—a finding made possible by years of international research.

Germline heterozygous BARD1 mutations found in different individuals with history of mesothelioma. (A) Survival plot showing percentage of survival vs. time in low and high BARD1 expression related ...

Patients with stages I to III breast cancer who were seen at a single cancer center between 2010 and 2012, and who agreed to participate in research DNA banking, were included (N = 488). Personal and ...

Cetuximab plus dalpiciclib in patients with HPV-negative, anti-PD-1-resistant recurrent or metastatic head and neck squamous cell carcinoma. Personalized biomarker-based treatment strategy in patients ...

Ovarian cancer is the 6th most common cancer in females in the UK, accounting for 4% of all new cancer cases in females (2017-2019). In females and males combined, ovarian cancer is the 16th most ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Undifferentiated spermatogonia, which form ...

May 20, 2025 — Trauma centers nationwide will begin to test a new approach for assessing traumatic brain injury (TBI) that is expected to lead to more accurate diagnoses and more appropriate ...

A NEW study presented at ESMO Breast 2025 explores the impact of inherited mutations in DNA repair genes on the effectiveness of cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) in hormone ...