PMR-116 shows promise in treating MYC-driven cancers, offering hope for patients with aggressive tumors in upcoming human trials. A promising new treatment to combat "undruggable" cancers has been ...

PIM protein kinases have been known for some time as oncogenes that promote lymphomagenesis together with MYC (c-Myc). It is now reported that PIM1 is a coactivator of MYC, and it phosphorylates ...

The presence of MYC translocation and high MYC mRNA expression have recently been associated with poor OS in patients with DLBCL treated with R-CHOP, raising questions about optimal management of ...

Both MYC amplification and high MYC protein expression have been associated with survival in exploratory studies. 8,11,13,23,24 The absence of prognostic value of MYC amplification in this study might ...

Applying a dual-engine approach that combines generative chemistry with advanced physics-modeling module AlChemistry, the research team identified and validated novel compounds with sub-micromolar ...

New York City mayoral race front-runner Andrew Cuomo was forced to fend off a volley of attacks from his Democratic primary rivals in a debate.

1 hour, 5 minutes. Several mayors joined policy advocates to discuss the Republican tax and spending cuts bill at the U.S. Conference of Mayors' annual meeting in Tampa, Florida.

Add to MyC-SPAN; Add program to calendar; Notify me when this airs ; Sign in to your MyC-SPAN account for airing and availability notifications. 11:00am U.S. House of Representatives: 06/20/2025.

Their time with the organization will be remembered through the traditional plaque donated by the MYC to the City, which will be displayed on the second floor of the Memorial Building near Council ...

(A) Schematic diagram illustrating sister chromatid cohesion mediated by the ring-shaped cohesin complex. (B) Nocodazole-arrested mitotic HeLa cells stably expressing Myc-Pds5A or Myc-Pds5B were ...

WD repeat domain 5 (WDR5) is a member of the WD40-repeat protein family that plays a critical role in multiple processes. It is also a prominent target for pharmacological inhibition in diseases such ...