Scientists have identified a biomarker for Alzheimer's that may help doctors spot the early signs of protein buildup in the ...
To determine the three-dimensional structure of small proteins ... the structures of other small and unstable proteins -- including the amyloid-beta peptide that builds up in the brain in ...
To determine the three-dimensional structure of small proteins ... the structures of other small and unstable proteins—including the amyloid-beta peptide that builds up in the brain in ...
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Structural analysis shows Alzheimer's disease mutation produces 'cottonwool' structures in the brain"We've demonstrated that the unique W-shaped structure of amyloid fibrils ... by mutations to the gene that encodes for the amyloid precursor protein," explains Yoshitaka Ishii of the RIKEN ...
Amyloid Precursor Protein’s Roles Outside of Alzheimer’s Disease Amyloid ... ultimately, a difference in cortex structure between mutant mice and controls. A recent study the lab carried out using ...
In addition to the formation of senile plaques and neurofibrillary tangles in brain, the pathological hallmarks of Alzheimer disease (AD), there is substantial neuronal and synaptic loss in the ...
Progress in deciphering the fundamental biological mechanism of Alzheimer's disease (AD) is proceeding at an impressive pace. A consensus has emerged among many investigators that cerebral ...
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