And the total protein was extracted from these samples. Primary myoblasts were added the ALA (A/+ group), transfected with ADIPOQ overexpression vector (A group) and siADIPOQ vector with addition of ...

On the other hand, knockdown of miR-3666 had the opposite effects in INS-1 cells. The bio-informatics analysis using TargetScan revealed that adiponectin (ADIPOQ) was a downstream target of miR-3666, ...

Notably, we also proposed that the interaction networks formed by miRNA, proteins and metabolites fingerprints involved in the early stage of DCM such as hsa-mir-122-5p, IL6, FGL1, LEP, ADIPOQ, INS, ...

Findings from the BHF PROTECT-TAVI trial indicate that the routine use of cerebral embolic protection devices during transcatheter aortic valve implantation does not decrease the incidence of ...

Endocardial cells are specialized endothelial cells that form the innermost layer of the heart wall. By virtue of genetic lineage–tracing technology, many of the unexpected roles of endocardium during ...

Despite multiple surgeries and extensive follow‐up, individuals with a univentricular heart have significant residual morbidity and mortality throughout life. By applying a state‐of‐the‐art ...

There is a general understanding of what constitutes the field of nutritional science. At its core, the discipline encompasses the provision of macro- and micro-nutrients, how they are processed in ...

Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common chronic liver disease globally and is currently estimated to affect up to 38% of the global adult population. NAFLD is a ...

The G-protein coupled receptors (GPCRs) activated by free fatty acids (FFAs) have emerged as new and exciting drug targets, due to their plausible translation from pharmacology to medicines. This ...