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In patients with IVDD, the levels of collagen II and aggrecan were decreased, whereas the expression levels of ADAMTS5 and MMP3 were increased (Figures 1D,E). These results indicated that PLK1 was ...
Cytokines regulate inflammation, autoimmunity and articular destruction in the joints of patients with rheumatoid arthritis. In particular, tumour-necrosis factor (TNF) has proved to be of ...
1 Raymond Purves Research Laboratories, Kolling Institute (University of Sydney) at Royal North Shore Hospital, Sydney, Australia 2 Camden Veterinary Hospital, University of Sydney, Camden, Australia ...
Aortic aneurysm is a complex pathology that can be lethal if not detected in time. Although several molecular mechanisms and pathways have been identified to be involved in aortic aneurysm development ...
Endocardial cells are specialized endothelial cells that form the innermost layer of the heart wall. By virtue of genetic lineage–tracing technology, many of the unexpected roles of endocardium during ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Kidney fibrosis, characterized by excessive ...
Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China Degenerative orthopedic diseases, as a global public health problem, ...
Correspondence to Professor Shiquan Sun, Xi'an Jiaotong University, Xi'an, Shaanxi, China; sqsunsph{at}xjtu.edu.cn; Professor Guangdun Peng, Chinese Academy of Sciences, Guangzhou, Guangdong, China; ...
Department of Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, Guangdong 518055, China ...