PIM protein kinases have been known for some time as oncogenes that promote lymphomagenesis together with MYC (c-Myc). It is now reported that PIM1 is a coactivator of MYC, and it phosphorylates ...

The research was published on Chemical Biology & Drug Design. The MYC protein is a well-established driver in up to 70% of human cancers, but has long been considered “undruggable” due to the ...

What's 6.85" big, has a massive 7,050mAh battery, an overclocked 4.47GHz Snapdragon 8 Elite SoC, 24 GB of RAM, and more RGB than a desktop PC? Oh, and has its own cooling fan? You (likely) guessed ...

New York City mayoral race front-runner Andrew Cuomo was forced to fend off a volley of attacks from his Democratic primary rivals in a debate Wednesday, with his opponents unleashing pent up ...

Here are the latest planning applications submitted to Basildon Council, featuring proposals for home extensions, commercial changes, and new residential developments across the borough. Among the ...

Amanda Becker ("Your Must Stand Up") and Colleen Long ("I'm Sorry for My Loss") examined the state of abortion access and reproductive healthcare in America. This was part of the 2025 Gaithersburg ...

Columbia University presented the Bancroft prize to the 2025 winners, authors Kathleen DuVal (Native Nations) and James Tejani (A Machine to Move Ocean and Earth). American History TV toured the ...

This morning will see plenty of sunshine. Through the afternoon, some patches of cloud will bubble up, but sunny spells will persist. Remaining dry. Tonight Tonight will be dry with largely clear ...

on June 14th G.O.S & District Audio team up for the first time to bring you THE party of the summer! CONDUCTA... one of the biggest headliners Cornwall has ever seen at an event like this, Along ...

When the sun's out, it's time to get high. Head for London's best rooftop bars and lofty terraces. We've rounded up the best for 2025. If you're reading this in spring/early summer, make sure your ...