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1Seoul National University, Seoul, Korea, Republic of.

Major Finding: Superkiller complex (SKIc) disruption via 9p21.3 deletion or high microsatellite instability leads to PELO dependency. Concept: Inhibiting PELO in SKIc-deficient cancers induces the ...

Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International ...

The NIH recently announced a cap of 15% on indirect costs for new grants. This plan has been temporarily blocked in federal court with a hearing scheduled for February 21. If cuts are implemented, ...

Immune checkpoint blockade (ICB) therapy has revolutionized cancer treatment, delivering impressive results across various cancers. However, resistance is common, and only a limited number of patients ...

Copyright held by the owner/author(s).

Major Finding: Myeloid-derived suppressor cells (MDSC) crosstalk with IDH–wild-type glioblastoma and promote tumor growth. Concept: Signaling between MDSCs and tumor cells support cell survival in ...

A Centers for Disease Control and Prevention (CDC) meeting on vaccines originally scheduled for next week has been postponed, according to a senior official from the Department of Health and Human ...

Cancer Immunotherapies (CITs) have shown unprecedented results in improving tumor control. However, many patients are still refractory to treatment. A deeper understanding of CIT-drugs mode of action ...

For authors of Research Articles that have been declined for publication at an AACR journal, the AACR offers the corresponding author the option to easily transfer manuscript files and supporting ...

Joan Jacob; Yasuaki Anami; Peyton C. High; Zhengdong Liang; Shraddha Subramanian; Sukhen C. Ghosh; Solmaz AghaAmiri; Cara Guernsey-Biddle; Ha Tran; Julie Rowe; Ali ...