Perilipin 5 has been implicated as a modulator of lipase activity and a scaffold linking lipid droplets to mitochondria. Here the authors show that PKA stimulates Peripilin 5 interaction with ...

Researchers from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences demonstrated the role of lipid droplet-localized CETN-SPDL1-L in the regulation of cone cell ...

Lipid droplets normally associate with mitochondria. But during an infection, these organelles seem to help switch cells into a bacteria-fighting metabolic mode by uncoupling themselves from the ...

Schematic describing how cAMP stimulation activates PKA, allowing PKA liquid droplet formation to compartmentalize the PKA activity and extra cAMP ...

Several proteins involved in the structural organization of the adipocyte lipid droplet (i.e., seipin, CIDEC, caveolin-1, and cavin-1) have been implicated in the pathophysiology of lipodystrophic ...

“Perturbations in lipid droplet morphology and function are related to many common diseases, such as diabetes, Alzheimer’s disease and fatty liver.” Salo's research is focused on the membrane protein ...

Mathew Blurton-Jones University of California, Irvine; Christel Claes [email protected]; Posted: 23 Aug 2019 This exciting new study by Marschallinger et al. defines and examines the age-dependent ...

When they overexpressed tau in glia, but not in photoreceptor neurons, lipid droplet production fell by nearly 80 percent. When they cranked up tau expression in glia throughout the fly brain, glial ...

Furthermore, some bacteria can evade the lipid droplet attacks, and these are often pathogens we are familiar with. “We had Salmonella in there, and there was no killing as far as we could tell ...