Dr. Rudnicki and his team discovered the exosome-targeting postal code or zip code within a protein called Wnt7a, which plays a critical role in development, growth, regeneration and cancer.

You have full access to this article via your institution. Figure 2: Wnt7a expression is downregulated in DES-exposed mice at the time of birth.

First, they showed that Wnt7a can attach itself to exosomes. Then, they deleted various parts of the Wnt7a protein until they found the smallest part that was responsible for exosome-targeting.