Paired BCR and TCR data were available for 542 individuals ... clustering of complementarity-determining region 3 (CDR3) sequences to identify disease-associated patterns, and 3) embeddings ...

The specificity of T cell recognition is determined by the variable (V) domain of the T cell receptor (TCR) α and β chains 1. TCR-peptide–MHC (pMHC) class I complexes for which crystal ...