SIRT6 acts as a powerful epigenetic regulator in spinal discs, and its absence leads to a cascade of degeneration-related events. Our work demonstrates that without SIRT6, disc cells enter a ...

The application, titled "Variants of SIRT6 for Use in Preventing and/or Treating Age-Related Diseases," was originally filed on 13 May 2022 and is jointly owned by the University of Rochester, The ...

LONDON, UK/ ACCESS Newswire/ February 20, 2025/ Genflow Biosciences Plc an emerging leader in the field of longevity research, focused on developing therapeutic solutions for the prevention of age ...

The randomized, controlled trial, conducted with CRO Syngene, involves 28 beagles aged 10+ years. In March, recipients received three different modalities of SIRT6 gene therapy with no ill or ...

SIRT6 regulates fat metabolism by activating another protein called peroxisome proliferator-activated receptor alpha (PPAR-alpha). This protein promotes the burning of fat in the liver.