The Rice team's new method, called RNA-addressable modification (RAM), bypasses these hurdles by using a synthetic catalytic RNA (cat-RNA) to "barcode" ribosomal RNA (rRNA) inside living cells.

Showing great promise in preclinical studies, PMR-116 disrupts a pathway downstream of MYC, inhibiting an enzyme that stunts the synthesis of ribosomal RNA (rRNA) – a process that's crucial in ...

Ribosomal RNA genes are essential for building ribosomes, the machineries that translate proteins. Ribosome biogenesis has long been known as a hallmark of cancer.

He zeroed in on Tetrahymena thermophila, a single-celled organism with an unusual genome. Each Tetrahymena carries thousands of copies of the gene for ribosomal RNA, a molecule that builds proteins.

These fragments showed strong sequence complementarity to ribosomal RNA and a leucine tRNA-derived fragment essential for protein translation (LeuCAG3′-tRF).

DNA’s chemical cousin, RNA, was the messenger that carries DNA instructions from the double helix in the cell’s nucleus to ...

In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...

Sequencing the glycoRNA molecules turned up hits for ribosomal RNA, transfer RNA, and small nucleolar RNAs, suggesting that they may be repurposed fragments of noncoding nucleic acids. Yet the rules ...