In contrast to RanT24N, RanQ69L has little effect on tRNA export, which does not require hydrolysis of the GTP on Ran (Fig. 2b, c) 9. Export of spliced mRNA also occurs efficiently in the presence ...

EXPORT MECHANISM: The tRNA must mature inside the nucleus before export. tRNAs are aminoacylated, and only tRNAs charged with an amino acid are exported efficiently. Export occurs when the tRNA is ...