A detailed picture of what happens when DNA transcription is paused early in the process has been obtained by structural ...

The researchers found that using a drug to inhibit RNA Polymerase 1 (Pol 1)—the enzyme responsible for human ribosomal RNA (rRNA) transcription—triggered a unique stress response that rewires ...

Known as promoter-proximal pausing, this interruption in the transcription activity of RNA polymerase II—the enzyme ...

This study reports two cryo-EM structures of the Nipah virus (NiV) polymerase L-P complex in its full-length and truncated ...

Laiho holds patents on RNA polymerase 1 inhibitors, which are managed by The Johns Hopkins University in accordance with its conflict-of-interest policies.

A Portrait of RNA Polymerase This multicolored molecular “cloud” is a 3D rendering of an enzyme known as RNA polymerase II that’s responsible for transcribing the genetic code from DNA into RNA.

A total of 513,134 RNA viral contigs were identified using the two methods, representing 161,979 potential viral species (with over 90% RdRP identity) and 180 RNA viral supergroups, comparable to ...

Scientists provide fresh insights on the origins of life, presenting compelling evidence supporting the 'RNA World' hypothesis. The study unveils an RNA enzyme that can make accurate copies of ...