Their role in cancer has garnered attention due to their potential as therapeutic targets. PPARs are categorized into three subtypes: PPARα, PPARβ/δ, and PPARγ.

After binding ligand, the PPAR-γ receptor heterodimerizes with the RXR receptor. Bexarotene (B) is a specific RXR ligand which has cytostatic properties similar to those of PPAR-γ agonists in vitro.

DC-SCRIPT, or dendritic cell-specific transcript, is a key regulator of nuclear receptor activity that may have prognostic value in breast cancer, according to a new study published online Dec. 14 ...

"RXR, the cell protein that keeps blood stem cells young and fit." ScienceDaily. ScienceDaily, 15 December 2022. <www.sciencedaily.com / releases / 2022 / 12 / 221215104602.htm>.