Items AP Nasus does not have a wide variety of items, mainly because he has to build AP and play a poke playstyle. His itemization is going to be similar to most poke mages in the game. There are ...

Nasus is a tank buster, so unless you are playing someone like Sion or Garen, stay away from the tanks. Instead, we want to look at champions that — shocker — disrupt him.