Employing the MMP library, the researchers were able to screen more than 23,000 single nucleotide mutations across 300 MMP strains and nominate candidate genes within a few days after identifying ...

The genes are called EREG, MMP-1, MMP-2 and COX-2. Massague's team suppressed each gene one by one and found a small effect.

Employing the MMP library, the researchers were able to screen more than 23,000 single nucleotide mutations across 300 MMP strains and nominate candidate genes within a few days after identifying ...