Mechanisms to separately regulate synaptic vesicle release and recycling Date: July 19, 2021 ... The temporal and spatial sequence of the incoming signals determines how information is processed ...

Shin et al. identify TBC1D23 as an adaptor that interacts both with golgins and endosomal WASH and is required for the delivery of endosome-derived vesicles to the trans-Golgi.

In order to investigate this process, the Heidelberg scientists looked for so-called ER-import sites (ERIS): special domains of the ER where incoming vesicles from the Golgi stacks fuse with the ER.

For the first time, scientists at Weill Cornell Medical College in New York City have observed in real time a cellular mechanism that's crucial to how brain cells communicate.

Based on studies with the V-ATPase inhibitor BafilomycinA1, lysosomal acidification is also thought to be required for fusion with incoming vesicles from the autophagic and endocytic pathways.

A new perspective article in ExRNA by Dr. Tiago Veit and colleagues highlights lipoproteins as potential RNA carriers in saliva, raising concerns about contamination in extracellular vesicle ...