Familial adenomatous polyposis (FAP) is a hereditary disease which, in addition to a high risk of bowel cancer, also a greatly increased risk of duodenal cancer.

The risk for inflammatory bowel disease is higher in patients with psoriasis or ankylosing spondylitis using IL-17A inhibitors than in those using apremilast, necessitating careful patient monitoring.

HSD promoted IL-17A production in mice. (A, B) Representative and quantified flow cytometry of IL-17A-producing cells by total lymphocytes in the spleen, peripheral blood, and brain tissues of HSD ...

IL-17A and IL-17F affect the pathogenesis of Crohn's disease and ulcerative colitis, although their precise role in the development of these disorders requires further characterization.

People with the hereditary disease familial adenomatous polyposis (FAP) have a greatly increased risk of developing a malignant tumor of the duodenum. Researchers have now discovered a mechanism in ...

People with the hereditary disease familial adenomatous polyposis (FAP) have a greatly increased risk of developing a ...

When we get sick, we often feel tired, moody, or anxious. Scientists have long known that this isn’t just about feeling ...

Experiments in mice showed that two cytokines, IL-17A and IL-17C, increased activity in the amygdala. When levels of these molecules rose, mice exhibited corresponding increases in anxiety-like ...