The risk for inflammatory bowel disease is higher in patients with psoriasis or ankylosing spondylitis using IL-17A inhibitors than in those using apremilast, necessitating careful patient monitoring.

HSD promoted IL-17A production in mice. (A, B) Representative and quantified flow cytometry of IL-17A-producing cells by total lymphocytes in the spleen, peripheral blood, and brain tissues of HSD ...

IL-17A and IL-17F affect the pathogenesis of Crohn's disease and ulcerative colitis, although their precise role in the development of these disorders requires further characterization.

Physicians have long observed a mystifying phenomenon: After a bout of infection or an autoimmune disease flare-up, some ...

Cytokines play a crucial role in connecting the immune system with the brain, affecting mood and behavior through ...

A new study published in The Journal of Immunology found that a high-salt diet (HSD) induces depression-like symptoms in mice by driving the production of a protein called IL-17A. This protein has ...

Cosentyx is the first interleukin-17A (IL-17A) inhibitor approved in Europe, providing a new first-line biologic treatment option for patients and has been shown as superior to Stelara and Enbrel ...

A new study published in The Journal of Immunology found that a high-salt diet (HSD) induces depression-like symptoms in mice by driving the production of a protein called IL-17A. This protein has ...

When these receptors bind to IL-17A and IL-17C, the neurons become more excitable, leading to an increase in anxiety. The researchers also found that, counterintuitively, if animals are treated with ...

Experiments in mice showed that two cytokines, IL-17A and IL-17C, increased activity in the amygdala. When levels of these molecules rose, mice exhibited corresponding increases in anxiety-like ...