Looking at the mechanism of CD6/ALCAM and the known importance of co-stimulatory pathways in the pathogenesis of SLE, I thought that lupus would be a potentially interesting area to focus on.

CONCLUSION: CD6+ TCD does not impede engraftment of unrelated bone marrow after low-dose TLI, cyclophosphamide, and TBI. CD6+ TCD as the sole form of GVHD prophylaxis results in an incidence of GVHD ...