Figure 1: The gene expression signature of latently HIV-1-infected quiescent CD4 T cells. VLP and viral particles were produced from mycoplasma-free 293T cells (ATCC CRL-3216) using the standard ...

A chronic hepatitis B (CHB) infection is characterised by host immune dysfunction related to a high viral antigen load. The restoration ...

Therefore, it would be very useful to identify a surrogate marker for tracking changes in mucosal CD4+ T cells which could be routinely measured in blood to predict responses to therapy ...

These test results were correlated with viral load and CD4 count in patients who were and were not receiving antiretroviral treatment. Results. The investigators observed the following ...

Findings indicate that frequent COVID-19 booster shots do not weaken T-cell responses, alleviating concerns for vulnerable ...

Both tests rely on taking routine blood samples from patients and then analyzing the blood for markers of the virus or of immune system functioning. The cheaper test looks at the abundance in the ...

Normally, T-cells with markers known as CD8 are cytotoxic, and those with the CD4 marker are not, so the authors first thought that perhaps CD8-positive cells were increased. But that turned out ...

the best surrogate markers for HIV disease progression and for decisions regarding antiretroviral therapy and, especially, prophylaxis of opportunistic infections should focus on the CD4+ cell ...

When naïve CD4-positive CD4+ T cells receive news of an infection elsewhere in the body, they become activated with additional cell-surface markers, and they differentiate in two directions, becoming ...