The Birch reduction is a reaction commonly used to make medicines and bioactive compounds, but the laborious process typically requires that chemists handle liquid ammonia, use cryogenic ...

Mechanochemical Birch Reduction with Low Reactive Alkaline Earth Metals Journal: Angewandte Chemie International Edition Published: 2024-04-03 DOI: 10.1002/anie.202319449 Affiliations: 2 Authors ...

The system developed could drive tough reactions like the Birch reduction, a reaction normally requiring liquid ammonia and alkali metals. It could also break a wide variety of chemical bonds, C ...

Mechanochemistry enabling highly efficient Birch reduction using sodium lumps and D- (+)-glucose Journal: Chemical Science Published: 2024-02-12 DOI: 10.1039/d3sc06052g Affiliations: 2 Authors: 3 ...

The hot electrons generated by this mechanism demonstrate remarkable potential for a variety of organic reactions, including the Birch reduction and the reductive cleavage of C-Cl, C-Br, C-I, C-O ...