Journal reference: Shiheido‐Watanabe, Y., et al. (2023). Porphyromonas gingivalis, a periodontal pathogen, impairs post-infarcted myocardium by inhibiting autophagosome–lysosome fusion.

The researchers found that transmembrane cargo receptors can initiate autophagosome biogenesis through two distinct pathways: one by recruiting the upstream FIP200/ULK1 complex and another by ...