A Thromboxane A 2 Receptor-Driven COX-2-Dependent Feedback Loop That Affects Endothelial Homeostasis and Angiogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology (2022). doi: 10.1161 ...

West JD, Galindo CL, Kim K, et al. Antagonism of the thromboxane-prostanoid receptor as a potential therapy for cardiomyopathy of muscular dystrophy. J Am Heart Assoc . 2019;8(21):e011902. doi: 10 ...

Up4A exerts its effects largely through activation of purinergic receptors, and its actions intersect with pathways involving cyclooxygenase (COX) and thromboxane receptors.

Cumberland Pharmaceuticals’ Duchenne muscular dystrophy (DMD) drug has improved the amount of blood pumped by the heart, hitting the main goal of a phase 2 trial. The active thromboxane receptor ...