A team led by Prof. CHEN Lingling from the Center for Excellence in Molecular Cell Science of the Chinese Academy of Sciences revealed a spatiotemporal separation in the processing of distinct rRNA ...

Other nucleolar noncoding RNAs have also been identified to function in pre-rRNA processing 41. Here we showed that risiRNAs suppress rRNA at least in part through the nuclear RNAi pathway.

A proposed model of the coordination of pre-rRNA processing, spatial distribution 949 and nucleolar sub-structures. Credit: bioRxiv DOI: 10.1101/2024.11.02.621631 ...

This article describes the production of 18S, 5.8S, 28s, and 5S rRNAs in eukaryotes, and post-translational modifications of tRNA and mRNA.

Structural basis of ribosomal RNA transcription regulation. Nature Communications, 2021; 12 (1) DOI: 10.1038/s41467-020-20776-y ...

The multi-gene family that encodes ribosomal RNA (the rDNA) has been the subject of numerous review articles examining its structure and function, as well as its use as a molecular systematic marker.

More information: Zhengping Shao et al. DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis, Nature (2020). DOI: 10.1038/s41586-020-2041-2 ...

This study sheds light on the molecular function of one of the enzymes with RNA helicase activity involved in the synthesis process of the large ribosome subunit. By combining biochemical, genetic ...