Focusing on PKA and dephosphorylation enzymes, the research group created comprehensive gene knockout mice and conducted further experiments inducing the expression of functionally modified ...

PKA-containing complexes can also regulate cardiomyocyte contraction when localized to the cytoskeleton, where these enzyme regulate mitochondrial activity necessary for contraction.

Focusing on PKA and dephosphorylation enzymes, the research group created comprehensive gene knockout mice and conducted further experiments inducing the expression of functionally modified ...

A-kinase anchoring proteins (AKAPs) target protein kinase A (PKA) to distinct subcellular locations. This positions the enzyme at regions of cyclic-AMP production and confines phosphorylation to a ...

That allows the researchers to see where in the cell the active enzyme is located. So this PKA sensor not only indicates whether the enzyme is on or off, but also locates where PKA is being turned ...

The enzyme protein kinase A (PKA) is responsible for many processes in a cell. The messenger ‘cyclic AMP’ activates PKA: adding it to the stem cells ensures that they stimulate one another ...

That allows the researchers to see where in the cell the active enzyme is located. So this PKA sensor not only indicates whether the enzyme is on or off, but also locates where PKA is being turned ...

Research conducted at the University of California, San Diego (UCSD) School of Medicine has shed new light on the structure and function of one of the key proteins in all mammalian cells, protein ...

Focusing on PKA and dephosphorylation enzymes, the research group created comprehensive gene knockout mice and conducted further experiments inducing the expression of functionally modified ...

Researchers have investigated how protein kinase A (PKA), an enzyme involved in choosing when and how much insulin is released by the pancreas, acts within the body. A team at the Johns Hopkins ...

Research conducted at the University of California, San Diego (UCSD) School of Medicine has shed new light on the structure and function of one of the key proteins in all mammalian cells, protein ...