Values can be accurately determined in the presence of impurities. The Software seamlessly integrates the collection of electrophoretic separation data, the calculation of compound pKa values, and the ...

Compounds that increase the activity of an enzyme called protein kinase A (PKA) improve long-term hippocampal-dependent memory in aged mice and have been proposed as possible therapeutics for ...

A key aspect of their chemistry is the balance of acidity and complex stability, where the pKa of boronic acids is around 9 ... reaction between a boronic acid and alcohols, leading to a compound that ...

The acid dissociation constant (pKa) has an important influence on molecular properties that are crucial to compound synthesis, formulation and optimization of absorption, distribution, metabolism and ...