H89 prevents the production of cholangiocarcinoma cells that is encouraged by PGE 2 via triggering the cAMP-PKA-CREB pathway. Bt 2 cAMP, also called dibutyryl-cAMP, activates the PKA directly and ...

BBPH, bear bile powder high dose; BBPL, bear bile powder low dose; DSS, dextran sulfate sodium; NC, normal control; 5-ASA, 5-Amino salicylic acid. Ulcerative colitis (UC) is a chronic autoimmune ...

Sure enough, BACE1 overexpression in mouse N2a neuroblastoma cells and rat primary cortical neurons reduced phosphorylated CREB. BACE1 also quashed protein kinase A (PKA), which phosphorylates CREB, ...

Specifically, stress-related neurotransmitters and obesity-related hormones were found to activate a protein called CREB, ...

Whenever scientists start looking at ways to maintain memory, some of the same names keep cropping up. Cyclic AMP-response element binding protein (CREB) and brain-derived neurotrophic factor (BDNF) ...