The glomerular filtration rate (GFR) assesses the function of all nephrons, and the single-nephron GFR assesses the function of individual nephrons. How the single-nephron GFR relates to demographi ...

Researchers are investigating which factors control the formation and function of specific segments of the nephron, called the distal nephron. Their findings could have implications in the ...

Single-nephron GFR varied little according to age, sex, and height of kidney donors. ... Kidney donors were in good renal health yet varied in sex, age, height, kidney function, ...

“Without NPCs, postnatal kidneys are unable to form new nephrons—hence the need for kidney transplantation once nephron function declines. However, there are simply not enough kidneys available for ...

Proper function of the kidney is critical for concentrating urine, regulating blood pressure, ... and colleagues set out to identify key regulators of distal nephron function.

Both studies focus on the progenitor and stem cells that form the kidney’s filtering units, known as nephrons, in embryonic mice. “Nephron progenitor cells cease to exist by the time humans are born,” ...