PHILADELPHIA -- Researchers long thought that only one strand of a double-stranded microRNA can silence genes. Though recent evidence has challenged that dogma, it's unclear what the other strand ...

To investigate how microRNAs are involved in neuron differentiation, the team developed new tools that temporarily turn off microRNA function during specific developmental windows. They found that ...

Function of microRNA activity by ActMiR in bladder cancer. Authors: Ana Collazo Lorduy, Mireia Castillo-Martin, Eunjee Lee, Jun Zhu, and Carlos Cordon-Cardo Authors Info & Affiliations Publication: ...

Some companies are even combining microRNA profiles with machine learning to enhance predictive power. It is a leap toward accessible, non-invasive diagnostics that can be used in routine screening.

Mantle Cell Lymphoma (MCL) represents only 5–10% of all non-Hodgkins lymphomas, making it an uncommon but difficult form of lymphoma to treat. It has the worst prognosis among the B cell lymphomas ...

El Fatimy, R., et al. (2022) A nuclear function for an oncogenic microRNA as a modulator of snRNA and splicing. Molecular Cancer. doi.org/10.1186/s12943-022-01494-z.

Dr. Yogesh Dwivedi authored a book chapter “microRNA Function and Dysregulation in Depression and Suicide” in Suicide Phenomenology and Neurobiology, Edited by: Keri Cannon and Thomas Hudzik.

In the October15th issue of G&D, Dr. Fen-Biao Gao and colleagues at UCSF report that microRNA-9a (mir-9a) regulates neural development in the fruit fly, Drosophila. Using loss-of-function analysis ...

MicroRNA therapeutics are oligonucleotides that modulate microRNA functions, correcting gene expression imbalances and associated pathways.

STOCKHOLM — The Nobel Prize in medicine was awarded Monday to Americans Victor Ambros and Gary Ruvkun for their discovery of microRNA, a fundamental principle governing how gene activity is ...